A MASH-inducing diet caused DNA damage in the liver cells (hepatocytes) of MUP-uPA mice. This triggered the DNA-damage response (DDR; a signalling pathway that repairs DNA damage and limits the ...
Composed mainly of hepatocytes, the position of these cells is key to their role and determines changes in their metabolism and aging profile. Researchers from the Max Planck Institute have conducted ...
To meet various application requirements, 3D-verified cells can be obtained for mono- or duo-culture. Tri-cultures are available as NASH-in-a-box kits. Mono-culture Primary human hepatocytes HBV ...