Molecular biologists decode the epigenetic silencing of problematic retroviral gene sequences. LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene ...

How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...

Histone deacetylation and other modifications, particularly the methylation of lysine 9 within histone H3 (H3-K9) residues located in the histone tails, cause chromatin condensation and block ...

While each cell contains the complete genetic blueprint of an organism, chemical marks on the DNA – so-called epigenetic ...

Liver diseases represent a significant global health challenge, encompassing a spectrum of conditions such as hepatitis, fatty liver disease, cirrhosis, and hepatocellular carcinoma. Recent ...

“Impact of air pollution exposure on cytokines and histone modification profiles at single-cell levels during pregnancy,” Youn Soo Jung, Juan Aguilera, Abhinav Kaushik, Ji Won Ha, Stuart ...

Epigenetic regulation relies on the dynamic modification of the two building blocks of chromatin: DNA and histone packaging proteins, to establish and maintain cell identity and fate. We develop and ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...