Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...

Combining these two sets, we identified 582 different human genes showing unequivocal alternative splicing via exon insertion, extension, truncation or deletion. This represents 22% of genes ...

The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...