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Pharmaceutical Technology
3 小时
Tinostamustine by Mundipharma EDO for Mantle Cell Lymphoma: Likelihood of Approval
Tinostamustine is under clinical development by Mundipharma EDO and currently in Phase I for Mantle Cell Lymphoma.
Nature
2 年
Bringing NHA HDAC6 inhibitors to the clinic for cardiovascular and neurodegenerative disorders
CKD is developing non-hydroxamic acid (NHA)-based histone deacetylase 6 (HDAC6) inhibitors for non-oncology indications. CKD’s NHA inhibitors address the limitations of hydroxamic acid (HA ...
Medical Xpress
1 个月
Cerebral stroke in animal models with hypertension found to affect arteries in other body ...
To address these changes, the team tested the administration of suberoylanilide hydroxamic acid (SAHA) during the restoration of blood flow. The drug successfully prevented some of the early ...
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