“Regeneration of immunocompetent B lymphopoiesis from pluripotent stem cells guided by transcription factors” ...

How are induced ... Cell Stem Cell 5, 584–595 (2009). Takahashi, K. & Yamanaka, S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Recent new technologies enabling the genetic modification of human embryonic stem cells and the derivation of patient-specific induced ... of defined transcription factors (Oct4, Klf4, Sox2 ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex ... which is best known as a tumor suppressor but also plays fundamental ...

It includes the use of induced pluripotent stem cells (iPSCs), reprogrammed cells, and cell culture in vitro. Tissue architecture techniques like 3D bioprinting and decellularized organs are shown, ...

In vertebrates, pluripotent stem cells only exist during early embryonic stages, driven by specific transcription factors (TFs ... such as in the generation of induced pluripotent stem cells ...