Signal binding to membrane receptor tyrosine kinases (RTKs) activates an enzyme called a kinase. Learn how kinases initiate a signaling cascade that relays information to the nucleus.

Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly observed in breast cancer cells leading to malignant cell ...

Recent data suggests a direct link between the surface estrogen receptor and the mitogen-activated protein (MAP) kinase signaling cascade. MAP kinases are a family of serine–threonine kinases ...

Discover recent research that sheds light on a promising therapeutic strategy for tackling prostate cancer by targeting the ...