He, H.J., Cen, X.H., Liang, Y.J., Zhong, J.M., Deng, J.H. and Jiang, Y.J. (2025) Progress in the Regulation of Lipid Metabolism by the Orphan Nuclear Receptor Nur77. Journal of Biosciences and ...

Recent advancements in understanding the molecular basis of the prostaglandin D2 receptor (DP2) have significant implications for developing new anti-inflammatory and anti-allergic therapeutics.

Reduced receptor-mediated catabolism of LDL causes high plasma LDL cholesterol (LDL-C) and premature coronary artery disease. Statins lower plasma cholesterol by upregulating LDL receptor gene ...

From combating cancer and infections to storing energy, lipid-protein interactions are critical to biological processes in ...

Furthermore, AGE engagement of the receptor for AGE (RAGE ... experimentally-induced alterations in glycemia, insulinemia and lipid profile. These findings indicate AGE–RAGE interaction ...

Lipid metabolism in homozygous familial hypercholesterolemia (HoFH) is abnormal owing to lack of functional LDL receptors, although residual receptor function between 2 and 25% is present in the ...

Yang Zhang, Ph.D., and Jinjun Shi, Ph.D., both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative ...

A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor ...

Yang Zhang, PhD, and Jinjun Shi, PhD, both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital, are co-senior authors of a ...

Study deciphers the molecular handshake between LDL receptors and apoB100, shedding light on cholesterol metabolism and its role in cardiovascular disease. Study: Structure of apolipoprotein B100 ...