The fight against cancer often begins with uncovering hidden players, and this study reveals one such key player: an ...

The discovery of lysosomes led to many new questions. The most critical question was: what was the physiological function of this "bag" of enzymes? The Function of Lysosomes One of the definitive ...

The fight against cancer often begins with uncovering hidden players, and a recent study reveals one such key player: an ...

Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells' digestive systems by getting rid of unwanted materials.

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Figure 1. Entosis promotes cell competition. (A) Entosis ...

The scientists found that, relative to late endosomes and lysosomes in APP-KI hippocampal neurons, these compartments in PSEN2-KO mice had less Aβ, and more β-CTF. In PSEN2-FAD mice, both Aβ and β-CTF ...