1,2 BIIB122 (DNL151) is a selective, central nervous system-penetrant small molecule inhibitor of LRRK2 that is hypothesized to improve lysosomal dysfunction. Denali’s strategic partner Biogen ...
1,2 BIIB122 (DNL151) is a selective, central nervous system-penetrant small molecule inhibitor of LRRK2 that is hypothesized to improve lysosomal dysfunction. Denali’s strategic partner Biogen is ...
Pathogenic mutations in LRRK2 account for 4-5% of familial and 1-2% of sporadic Parkinson’s disease. 1,2 BIIB122 (DNL151) is a selective, central nervous system-penetrant small molecule inhibitor of ...