Patients carrying the SF3B1 mutation, who were positive for ring sideroblasts ... across various populations of patients who have MDS. "The [hematological improvement-erythroid] response in ...

Moreover, while Reblozyl was only cleared for use as second-line therapy in MDS patients with ring sideroblasts – blood cells with a characteristic circle of iron deposits around their nucleus ...

MDS are a group of closely related blood cancers ... week in adult patients with IPSS-R myelodyplastic syndrome with ring sideroblasts (MDS-RS) or myeloproliferative neoplasm with ring ...