Mast cell leukemia (MCL) is a rare type of blood cell cancer. It causes the body to produce a large number of mast cells that can affect different areas of the body. MCL is a subtype of mastocytosis.

It may also progress to ASM or mast cell leukemia (MCL) over time. Close monitoring is essential. ASM involves a rapid and extensive accumulation of abnormal mast cells in multiple organs ...

The researchers found that a compound called SYM2081 inhibited inflammation-driving mast cells in mouse models and human skin samples, paving the way for new topical treatments to prevent itching ...

Systemic mastocytosis (SM) is characterized by an abnormal accumulation of mast cells, a type of immune ... DeAngelo, MD, PhD, Chief of the Division of Leukemia at Dana-Farber, who presented ...