Second-line: (previously treated with sulfonylurea or metformin only): 2.5mg/500mg or 5mg/500mg twice daily (AM & PM) (initial dose should not exceed previous daily doses of individual components ...
Previously on metformin alone: Saxagliptin/metformin ext-rel should provide current metformin dose. Max saxagliptin 5mg/day and metformin ext-rel 2000mg/day. Renal impairment (eGFR 30–45mL/min/1 ...
Cumulative metformin exposure is strongly associated with the severity of peripheral neuropathy in patients with type 2 diabetes mellitus (T2DM), show Daryl Wile and Cory Toth at the University of ...
Serious side effects of metformin are rare. Less serious side effects, like digestive issues and headaches, are common, but these usually go away with time. You can reduce the chances of side ...