Methotrexate sodium 2.5mg; scored tabs. Be fully familiar with this drug's toxicity before use. Obtain baseline and monitor CBCs for myelosuppression, and hepatic, renal and pulmonary function ...

Initially 12g/m 2 IV infusion over 4 hours; may be increased to 15g/m 2; see literature for leucovorin rescue dosing with high-dose methotrexate. Be fully familiar with this drug's toxicity before ...

The use of high-dose methotrexate (HD-MTX) has improved survival rates. This article describes the experience of a patient treated with HD-MTX and outlines the essential aspects of care for the ...

The COBRA schedule comprised hydroxychloroquine (400 mg per day), sulfasalazine (2 g per day), methotrexate (10 mg per week) and high-dose prednisolone (60 mg per day tapered to 7.5 mg per day).

Randomized Trial of Enhanced Versus Standard Navigation to Promote Timely Initiation of Adjuvant Radiotherapy for Head and Neck Cancer Shaff et al 1 are to be congratulated on their study showing that ...

USA: A recent study published in the Blood Journal revealed that patients with methotrexate-associated acute kidney injury ...

Management of Malignant Pleural Effusion in 2024: A Definitive and Unified Global Approach We appreciate the kind words from Cohen 1 regarding the impact of our study but disagree with his ...

Nat Clin Pract Rheumatol. 2007;3(1):26-34. Slow transport via folate receptor (lower affinity for methotrexate than for folic acid) Increased drug efflux via ATP-binding cassette (ABC) subfamily ...