Firstly, leflunomide can be used as a first-line DMARD in patients with RA who cannot tolerate methotrexate or for whom this drug is contraindicated. Secondly, the data from the BeSt study showed ...

has been used for rheumatoid arthritis (RA) treatment since 1980. It is the most common effective disease-modifying antirheumatic drug (DMARD) for RA, and is considered to be the anchor drug ...

than low-dose methotrexate for the treatment of rheumatoid arthritis (RA). Administration of chicken CII is thought to induce peripheral immunological tolerance to CII, the main constituent of ...

But looking back at the time, when all we could do was to suppress the pain, there has been great advancements in treating rheumatoid arthritis.

Yes, according to a randomized trial — but with caveats. By 2 years, primary radiographic assessment showed that the percentage of patients without evidence of joint damage was significantly ...

Initially 12g/m 2 IV infusion over 4 hours; may be increased to 15g/m 2; see literature for leucovorin rescue dosing with high-dose methotrexate. Be fully familiar with this drug's toxicity before ...