Daily oral treatment with T-614, a member of the methanesulfonanilide family of cyclo-oxygenase 2 inhibitors, might be an alternative to weekly methotrexate therapy for rheumatoid arthritis (RA).

Methotrexate (MTX) remains a cornerstone in the treatment of rheumatoid arthritis, despite the advent of newer biologic therapies, because of its long-term efficacy and safety. However ...

Methotrexate is a cornerstone of therapy worldwide for juvenile idiopathic arthritis, yet there remains vast variability in drug dosing and administration, as well as unpredictable outcomes on the ...

Patients with late-onset rheumatoid arthritis face poorer physical outcomes and higher risks of death and malignancy, ...

Methotrexate sodium 2.5mg; scored tabs. Be fully familiar with this drug's toxicity before use. Obtain baseline and monitor CBCs for myelosuppression, and hepatic, renal and pulmonary function ...

Early treatment escalation to biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) following methotrexate (MTX) failure in new-onset rheumatoid arthritis (RA) does not ...

Differences in rates of bDMARD treatment initiation among US veterans with RA living in rural vs urban areas cannot be fully explained by location.