The precise mechanism of action of metronidazole is unclear. Infuse over 1hr. Anaerobic infections: 15mg/kg (loading dose), then 7.5mg/kg every 6hrs for 7–10 days; max 4g/24hrs. Bone/joint ...

Metronidazole exerts antibacterial effects in an anaerobic environment against most obligate anaerobes. Once metronidazole enters the organism by passive diffusion and activated in the cytoplasm ...