In F2 screens, a mutagen, such as ethylnitrosourea (ENU), is used to generate hundreds of point mutations in the male pre-meiotic germ cells (spermatogonia). ENU-treated males are crossed to wild ...

A genetic screen is screen is a laboratory procedure ... Mutations can be introduced into an organism's genome by exposing the organism to a mutagen, which is an agent that changes the DNA.

In the Chernobyl Exclusion Zone, worms show no genetic damage despite living in highly radioactive soil, and free-ranging ...

One of the most important breakthroughs in the history of genetics was the discovery that mutations can be induced by physical and chemical mutagens (agents that change the genetic material of an ...

5. Easier to introduce genetic changes Introducing genetic changes in zebrafish is straightforward using chemical mutagens and other tools such as CRISPR. Zebrafish are able to withstand much higher ...

A large team of contributors and editors working under the auspices of the United Kingdom Environmental Mutagen Society (UKEMS) have contributed a wealth of first-hand experience in compiling this ...