there is no doubt that multiple sclerosis affects both myelin and axons. The discovery that the ubiquitin proteasome pathway is involved in Wallerian degeneration suggests that an autodestruction ...

Patients with MS develop various symptoms ... Brophy, P. J. Mechanisms of axon ensheathment and myelin growth. Nature Reviews Neuroscience 6, 683–690 (2005).

The pathophysiology of multiple sclerosis (MS) is characterized by demyelination ... The retina is unique within the CNS in that it contains axons and glia but no myelin, and it is, therefore ...

An investigational drug for multiple sclerosis from Io Therapeutics has restored leg mobility and myelin nerve coatings in mice, the biotech announced Dec. 23. The Texas-based company conducted ...

Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive and permanent ...

Biochemical, transcriptional and histological measurements in spinal cord supported that these gait improvements reflected increased axon survival ... the discovery of restorative neural therapeutics ...

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics ...

Dr. Robertson stated “These results inform the discovery of restorative neural therapeutics for MS by demonstrating that selective RXR agonism is sufficient for effective myelin repair.

Parts of these neurons are protected by an insulating layer called a myelin sheath. If you have multiple sclerosis (MS), your immune system attacks these myelin sheaths as if they were invaders.

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the ...