there is no doubt that multiple sclerosis affects both myelin and axons. The discovery that the ubiquitin proteasome pathway is involved in Wallerian degeneration suggests that an autodestruction ...

Patients with MS develop various symptoms ... Brophy, P. J. Mechanisms of axon ensheathment and myelin growth. Nature Reviews Neuroscience 6, 683–690 (2005).

An investigational drug for multiple sclerosis from Io Therapeutics has restored leg mobility and myelin nerve coatings in mice, the biotech announced Dec. 23. The Texas-based company conducted ...

Scientists say IRX4204 given to mice with evident symptoms showed potential "as a remyelinating and neurorestorative ...

Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive and permanent ...

Dr. Robertson stated “These results inform the discovery of restorative neural therapeutics for MS by demonstrating that selective RXR agonism is sufficient for effective myelin repair.

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics ...

Effects of withdrawal in EAE Clinical study Phenytoin Treatment of epilepsy Protects axons ... encephalomyelitis; MOG, myelin oligodendrocyte glycoprotein; MS, multiple sclerosis.