In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

South San Francisco biotech Pionyr was sold two years ago. Now three of its leaders want to test a trio of drugs beyond ...

making it difficult to understand their organizational patterns in live tissue. The discovery of joint localization between club-like and myeloid cells would not have been possible without this ...

Deep characterization of myeloid cell subsets by single cell RNA ... studies and compartments—such as in blood versus synovial tissue—has not yet been systematically investigated.