Heart failure is the terminal stage of various cardiovascular diseases, usually characterized by pathological myocardial ...

Another active area of research in the laboratory focuses on unraveling the mechanisms behind maladaptive, or pathological, and adaptive, or physiological, cardiac hypertrophy. In response to certain ...

HCM is typically characterized by asymmetric myocardial hypertrophy, which is often associated with diastolic dysfunction, LV outflow tract obstruction and mitral regurgitation. Myocardial cell ...

The natural history of HCM is highly diverse and depends on a variety of factors including degree of myocardial hypertrophy and fibrosis, as well as severity of LVOT obstruction. [10] Marked ...

Aim Differentiating physiological cardiac hypertrophy from pathology is challenging when the athlete presents with extreme anthropometry. While upper normal limits exist for maximal left ventricular ...

You have full access to this article via your institution. Though activation of the calcineurin pathway can produce cardiac hypertrophy in transgenic mice 3, the results of our study indicate that ...

MEDLINE 5. Maron BJ, Roberts WC: Quantitative analysis of cardiac muscle cell disorganization in the ventricular septum of patients with hypertrophic cardiomyopathy. Circulation 1979; 59: 689–706.

Hypertrophic cardiomyopathy, or HCM, is a genetic disease in which the heart muscle grows thicker than normal. You might ...

More information: Xiang Nie et al, lncRNA ZNF593-AS inhibits cardiac hypertrophy and myocardial remodeling by upregulating ...

Cardiovascular system Cardiac hypertrophy; increased stroke volume (SV); decrease in resting heart rate (HR); increase in maximum cardiac output (Q); capillarisation at the lungs and muscles ...