The first pathological descriptions of the disease 150 years ago already showed that demyelinated axons could degenerate ... the book covers the physiology of nerve impulse propagation before ...

Axon guidance is the pathfinding step that enables axons—the longest part of a neuron, through which the nerve impulse is propagated outside the cell—to be correctly directed to their target.

An example of PNS myelinated nerve fiber is shown. (B) Illustration of transverse section of myelinated axon at the internode. (C) Light microscopy of a mouse sciatic nerve at lower magnification.