PAT-DX1 then penetrates the cell nucleus where it binds to sites of damaged nuclear DNA, inhibiting DDR processes (Fig. 1). The degree of inhibition is modest and insufficient to kill normal cells ...

Radiation -induced mutations may not be the reason for the genetic differences between dog populations living near the ...

When it comes to identification with DNA, forensic scientists have two basic approaches at their disposal. One approach analyzes nuclear DNA and is useful in identifying someone who is alive or ...

Histones are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin. Nuclear DNA does not appear in free linear strands; it is highly condensed and ...

Rex Heuermann's attorneys say DNA results from hair found in six of the crime scenes should be excluded from the trial.

With the exception of red blood cells, which contain no nucleus and no nuclear DNA, every one of these cells contains the human genome -- a string of three billion A's, C's, G's, and T's.

Plastic chemicals may harm DNA, as new research reveals how additives disrupt nematode egg formation, suggesting risks to ...

Rex Heuermann's attorneys want to exclude certain DNA testing as evidence, arguing the technique used has not been generally ...

CNL’S CNRI-H PROGRAM CONTINUES STRONG GROWTH THANKS TO NEW PROJECTS WITH REPARE THERAPEUTICS AND DEFENCE THERAPEUTICS ...

Decades ago they witnessed nuclear weapons tests in the South Pacific. Now some veterans hope new DNA testing will prove it was responsible for their subsequent ill health, which they say ruined ...

The Sfeir lab seeks to understand basic chromosome biology and how their mismanagement manifests in disease. Our research is focused on three major areas: telomere maintenance, nuclear DNA repair, and ...