Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...

近日，一篇发表在国际杂志Journal of Experimental & Clinical Cancer Research上题为“Selective metabolic regulations by p53 mutant variants in pancreatic cancer”的研究报告中 ...

Aa Aa Aa It seems nearly impossible for a normal cell to become a cancer cell unless it inactivates the p53 network. Our current understanding of this network has come from diverse lines of ...

We also demonstrated that, in vivo when the ligand-liposome encapsulated wt p53 was injected I.V., preexisting SCCHN and prostate cancer xenografts completely regressed after radiotherapy.

Researchers in Michael Sigals lab at the Max Delbruck Center and Charite - Universitatsmedizin Berlin have discovered the ...

Scientists at Indiana University School of Medicine have discovered a new way to attack prostate cancer by cutting off its ...

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When cell growth gets out of control and malignant cells begin to proliferate, cancer can develop in a process known as ...

New research by a team of Indiana University School of Medicine scientists and their collaborators has uncovered a novel ...

The human body contains proteins that are designed to protect us from cancerous growths. Like most proteins, to do their job properly, these “guardians” have to fold into a specific three-dimensional ...

Research has uncovered a vulnerability in prostate cancer animal models that starves prostate tumors of critical nutrients and stunts their growth, which could lead to the development of new ...

They state, "In lung cancer p53 mutations have been found in 56% of tissue samples, and in colorectal, esophageal, ovarian, pancreatic, and skin cancers, prevalences of 44-50% have been reported." ...