Caspase 8 signals through the formation of a ... The tumor suppressors p53, pRb and p16 INK4a are normal in NB tumors with MYCN gene amplification and 1p36 loss of heterozygosity, yet cell growth ...

本文研究阐明了p53 R270H和p53R172H两种突变对胰腺导管腺癌细胞代谢的突变特异性影响。 当细胞生长失控时，恶性细胞就会开始增殖，癌症就会在 ...