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腾讯网
8 天
Nature Genetics | 从守护者到叛徒:如何重塑失职的TP53基因?
引言癌症背后的分子机制一直是科学研究的热点。在癌症的众多驱动因素中,TP53基因被誉为“基因组的守护者”,是人类体内最重要的肿瘤抑制基因之一。然而,这位“守护者”也常常成为癌症发展的“叛徒”,数据显示,大约50%的癌症患者都携带TP53基因的突变。这 ...
腾讯网
2 天
有效且安全!国外学者发文:感染预防和癌症治疗有前景的方法
【导读】用于信使核糖核酸(mRNA)递送的脂质纳米颗粒(LNPs)已取得显著进展,但脂质纳米颗粒介导的脱氧核糖核酸(DNA)递送在临床上仍面临诸多挑战。1月13日,美国贝勒医学院研究人员在期刊《Molecular Cancer》上发表了研究论文,题为 ...
Nature
3 个月
Analysing differential gene expression in cancer
It turned out that the increase in the expression of the p53 protein was caused by the stabilization ... which allow a smaller amount of mRNA samples to be analysed. One of the greatest advantages ...
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