Interestingly, however, when the authors studied cells expressing a dominant-negative ... found that MAPL-positive vesicles colocalize with peroxisomes, whereas TOM20-positive vesicles do not.

They discovered that HSR201 is located in peroxisomes, small cell compartments responsible for metabolic processes and that its localization is mediated by a unique targeting signal essential for ...

The US Food and Drug Administration has granted orphan drug designation (ODD) to Tempest Therapeutics' oral, selective ...