As it turns out, phagocytes ingest substances both for feeding and as a protective mechanism ... whether the uptake involves large particles (phagocytosis) or mainly solutes and water (pinocytosis).
The autophagy protein microtubule-associated protein 1 Light Chain 3 (LC3) becomes lipidated onto macropinosomes, phagosomes, and entotic vacuole membranes in a manner requiring core autophagy genes ...
HK) presented the mechanism of action (MOA ... with its ligand SIRPα on innate immune cells to inhibit tumor phagocytosis. Claudin 18.2 (CLDN18.2), a tight junction protein, is abnormally ...
Exerting Antitumor Effects through Multiple Mechanisms Research shows that AK132 binds with high affinity and specificity to human CLDN18.2 and human CD47, competitively blocking the interaction ...