A new study reports that mirodenafil, a newly developed oral phosphodiesterase type 5 (PDE5) inhibitor, is an efficacious and safe treatment for erectile dysfunction (ED). Many men with ED ...

Like other prescription medicines, Viagra and its generic form, sildenafil, work best when you take them under the right ...

Objective: To review available literature evaluating the pharmacology, pharmacokinetics, clinical efficacy, and adverse effects of cilomilast, a selective phosphodiesterase-4 (PDE4) inhibitor.

Topical antifungals, although often effective, are being discouraged in the early treatment of seborrheic dermatitis now that ...

The cyclic nucleotide phosphodiesterase 4 (PDE4 ... However, none of the PDE4 inhibitors tested so far has reached the market, mainly owing to tolerability issues such as emesis.

Bhopal: A 27-year-old man died of a cardiac arrest during his stay at a hotel in Gwalior. Police suspect that an overdose of the drug, combined with alcohol, led to the fatal incident. The man, ...

The introduction of phosphodiesterase-5 inhibitors (PDE5Is) in the market, such as generic Levitra, has revolutionized the ...

Zoryve is under clinical development by Arcutis Biotherapeutics and currently in Pre-Registration for Psoriasis.

Additional studies showed a role for the Cgs2 phosphodiesterase that hydrolyzes cAMP to AMP ... We have completed HTSs for PDE4, PDE7, PDE8, and PDE11 inhibitors. The compounds identified in these ...

Sildenafil is an ingredient known as a Phosphodiesterase Inhibitor (PDE-5) found in FDA- approved products for the treatment of male erectile dysfunction. According to the FDA, consumption of ...

Objective: Given the therapeutic and non-therapeutic use of the tadalafil, (phosphodiesterase-5 inhibitor, PDE-5i), we examined its effects on anaerobic performance indices. Methods: In total, 12 well ...