No writing assistance was utilized in the production of this manuscript. Plasmacytoid dendritic cells (pDCs) are specialized APCs. Compared with other APCs, pDCs express a high level of TLR9 and ...
In the autoimmune disease systemic lupus erythematosus (SLE), stimulation of Toll-like receptors (TLR) 7 and 9 by self nucleic acids is postulated to induce plasmacytoid dendritic cells (PDCs ...
is revealed to function as an intracellular DNA-binding protein that controls TLR9 activation in plasmacytoid dendritic cells (pDCs). This discovery provides insights into the functional ...