Left unchecked, VWF molecules trap passing platelets and promote the development of tiny clots. Normally, ADAMTS13 acts as a natural scissor, keeping VWF pruned back. “When these long VWF ...

When there’s an injury that’s bleeding, platelets gather at the site of the injury, forming a mesh to reduce the blood flow. Von Willebrand’s factor is a protein complex made up of several ...

vWF plays a key role in platelet adhesion and aggregation, especially under high shear conditions. vWF binds to GPIbα of the GPIbα–GPIX–GPV receptor complex of the platelet surface.

Any abnormality in your platelet function Conditions that cause insufficient platelet factors, such as von Willebrand factor (VWF) Contact your healthcare provider if think your heavy bleeding and ...

Various grades of bleeding manifestations have been defined by World Health Organization (WHO) but, there are few guidelines ...

Haemostasis is the prevention of unwanted blood loss; learn how this process works and is interrupted by blood-clotting ...

Experiencing a bloody nose can often feel like a minor, irritating event. For many, it's nothing more than a sudden ...

VWF Bancorp, Inc. operates as the holding company for Van Wert Federal Savings Bank that primarily engages in originating loans and accepting deposits in Van Wert, Ohio. The company’s deposit ...

Von Willebrand Disease in dogs is a complex clotting disorder that can vary in symptoms and the risk of genetic inheritance. Our vet explains ...

Platelets play an important role in atherothrombotic disease. The currently available antiplatelet drugs target key steps of platelet activation including thromboxane A 2 synthesis, ADP-mediated ...