Crish and Robert L. Eckert, which discloses the isolation and sequencing of the promoter sequence of human involucrin (hINV), a protein that interacts with keratin within epithelial cells.

Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

with the first referring to the generally recognized E1 and E2 boxes and the second number representing all CANNTG sequences up to position –400 or the 5' limit of available promoter sequence.