For example, the results of a study reported on page 291 of this issue of Nature Structural Biology shed light on a particular enzyme involved in prostaglandin metabolism. Information such as this ...
COX-2 is involved in prostaglandin synthesis and expressed throughout the nervous system, where it participates in pain sensitivity and in synaptic plasticity. Microsomal prostaglandin E synthase ...
Recent advancements in understanding the molecular basis of the prostaglandin D2 receptor (DP2) have significant implications for developing new anti-inflammatory and anti-allergic therapeutics.
Medically reviewed by Marissa Sansone, MD Ibuprofen and meloxicam are both nonsteroidal anti-inflammatory drugs (NSAIDs) that ...
We searched MEDLINE and the Cochrane Library between 1980 and November 2010 using multiple terms and combinations, including labor, induced/or induction of labor, prostaglandin or prostaglandins ...
More than 45 randomized trials including more than 5400 women have found vaginal misoprostol to be more effective than oxytocin or vaginal prostaglandin E2 at effecting vaginal delivery within 24 ...
Vorbipiprant sodium is under clinical development by Rottapharm Biotech and currently in Phase II for Gastrointestinal Tumor.
Overall, these findings suggest that angiotensin II-AT1 and prostaglandin E2-EP1 systems could be novel therapeutic targets for hypertension-induced dementia. Prof. Mouri concludes by saying ...
Bimatoprost is under clinical development by Laboratoires Thea and currently in Phase III for Ocular Hypertension.