Vane's contributions include showing that one of the world's most widely used drugs — aspirin — acts to relieve pain, fever and inflammation by blocking the production of prostaglandins.
These prostaglandins cause the tissue to swell. They also amplify the electrical signal coming from the nerves. Basically, they increase the pain you feel. NSAIDs work on a chemical level.
Pain is the stimulation of nerve endings, either due to swelling or release of prostaglandins, and painkillers work on the same pathway to the pain. Dr Mary Joan McLeod 2. Painkillers follow the ...
Prostaglandins (PGs) are ubiquitous compounds found throughout the body, including the eye. They are involved in a variety of ocular functions, two of which are intraocular pressure (IOP ...