The sequence of amino acids in the chain determines how the chain will fold up to make the protein, so different proteins have different three-dimensional shapes. The three-dimensional shape of a ...

and the related questionof how proteins and other molecules reach and stay at their specific subcellularlocations, are among the most difficult and exciting problems in cell biology.Three recent ...

Selective protein degradation by the ubiquitin–proteasome pathway is a fundamental regulatory strategy that fulfils essential roles in various cellular processes. In recognition of the central ...