The mechanistic (or mammalian) target of rapamycin (mTOR) signaling pathway, implicated in rapid antidepressant effects, was ...

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions ...

By the age of 35, fertility rates drop significantly, with only about 66% of women able to conceive. As women approach ...

The drug blocks the activity of a protein known as mammalian target of rapamycin (mTOR), which promotes proliferation through the activation of proteins such as S6 kinase. Although the mTOR ...

Yale researchers identified an underactive mTOR pathway as a cause of lissencephaly and reversed brain malformations in ...

Researchers have identified a molecular mechanism driving the structural abnormalities leading to lissencephaly that have ...

Rapamycin is a kind of inhibitor that works in the way it inhibits the mTOR (mechanistic target of rapamycin) complex 1 that is involved in the regulation of cell growth and aging. Studies have ...

Their findings pointed to dysregulation in the mTOR (mammalian target of rapamycin) pathway in both types of lissencephaly ...

Alfa, MD, discusses neratinib and its use as a monotherapy and in combination with immune checkpoint inhibitors and/or mTOR ...