Researchers have discovered that weak molecular interactions are crucial for initiating autophagy, the process of recycling ...

And it also degrades and recycles proteins when cells become starved. As a result, it plays a role in maintaining the constant environment in the living body. *2 selective autophagy Traditionally, ...

"This result is promising because it shows that we can specifically intervene in the autophagy of cargo molecules of living ...

Cells degrade components that are no longer needed through autophagy. New results show that a weak molecular interaction is ...

Aging involves gradual functional decline across various biological systems, including impaired cellular mechanisms such as ...

We are driven to understand the signals regulating tissue-specific autophagy signalling in mammalian health and disease. Understanding the physiological regulation and significance of selective ...

Autophagy is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Japanese ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...