Since two gene therapies were approved for sickle cell disease in late 2023, only a handful of patients have started the ...

The disease occurs when red blood cells, normally shaped like doughnuts, mutate into a sickle-shaped hindering oxygen distribution in the body. Bea Files, MD After the cell delivers oxygen to ...

“Even as the potential of in vivo gene therapy for sickle-cell disease takes shape over the coming years, today’s patients need better treatments now,” stresses Alexis Thompson, chief of the ...

A smear of this patient's blood showed that "the shape of the red cells was very irregular, but what especially attracted attention was the large number of thin, elongated, sickle-shaped and ...

Sickle Cell Disease is a genetic blood disorder that affects millions worldwide, primarily individuals of African, ...

Sickle cell anemia causes a person’s red blood cells to become sickle-shaped rather than disc-shaped, which can result in pain, breathing difficulties, and other complications. Sickle cell ...

However in people with sickle haemoglobin, the haemoglobin forms into long rigid chains. These chains distort the cell membrane into odd shapes - often like the shape of the old-fashioned farming ...

In The Pitt Season 1 Episode 2, sickle cell disease (SCD) is the main focus, as it brings to light the tough medical and racial challenges that people with this illness have to face every day.

When someone inherits two mutant copies of the hemoglobin gene, the abnormal form of the hemoglobin protein causes the red blood cells to lose oxygen and warp into a sickle shape during periods of ...

The sickle-shaped cells clog blood vessels and harm organs. Some victims die in childhood or have regular painful episodes. You can join the DKMS register if you are aged 17 to 55 and in ...