I am studying Laing Distal Myopathy (MPD1), an inherited condition that causes progressive muscle weakness in the extremities and has no cure. MPD1 is caused by mutations in β-myosin, the primary ...

Researchers at Johns Hopkins University School of Medicine have identified a subgroup of patients with necrotizing myopathy who have a novel autoantibody specificity that makes them potential ...

Statin therapy has proven efficacy for reducing the incidence of major adverse clinical events, but when administered in high doses these agents can cause myopathy. A means to identify those at ...

Skeletal muscles come in a variety of shapes and sizes, each tuned to a particular function — from the muscles that allow a person to run to those that focus the eye. Individual muscles also have ...

More information: Cecilia Leijding et al, Serum from patients with idiopathic inflammatory myopathy induces skeletal muscle weakness, Annals of the Rheumatic Diseases (2024). DOI: 10.1136/ard-2024 ...

Additionally, Capricor (CAPR) announced changes to its Phase 3 HOPE-3 clinical trial, noting plans to expand the drug's label ...

Cardiac muscle damage should also be considered when skeletal myopathy occurs. After a single oral dose of 5g, mean ± SD peak plasma concentrations (164 ± 28mcg/mL) were reached within 1.2 ± 0. ...