These issues are largely resolved by using iPS stems cells that arise from somatic cells because they can be recovered from an adult source. Furthermore, if cells are recovered from a human donor ...
In the summer of 2018, 59-year-old David Gould went for his annual checkup, expecting to hear the usual: Everything looks fine. Instead, he was told that he was newly—and oddly—anemic.
soma cell fate decision during embryogenesis. After a flurry of cell divisions from the starting “germ cell” (i.e. united egg and sperm), somatic cells begin to exit the cell cycle as the DREAM ...
The Nematode C. elegans, aka the worm, is a powerful system to approach the question. The adult worm consists of 959 somatic cells that arise via an invariant cell lineage. The invariant lineage ...
Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...