Thus, understanding the interplay between structure, dynamics and function of enzymes in solution is an important goal in modern biochemistry. Generations of students have been introduced to this ...

The goal of my research is to understand the mechanisms and structures of enzymes that perform and regulate essential nucleic acid transactions. My research integrates diverse experimental approaches ...

My major research interest is in enzymes, how they function, their mechanism of action, and how they, or inhibitors of enzymes, can potentially mitigate disease, either by modifying the structure of a ...

The researchers used genetic engineering approaches to modify the molecular structure of an enzyme—"Ado." Ado is originally an oxidase enzyme that adds an oxygen atom to the substrate—isoeugenol.

distinguished professor of chemistry and of biochemistry and molecular biology in the Eberly College of Science at Penn State and the leader of the research team. “The function of RNA enzymes is ...