The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

However, in the half-century since the structure of DNA was first elaborated ... Generally, those RNA molecules that do not take the form of mRNA are referred to as noncoding, because they ...

(Image: ttsz/iStock via Getty Images Plus) The Role of mRNA in Gene Expression Messenger RNA is an essential component of the gene expression process, which involves the conversion of genetic ...

Genetic variants can produce phenotypic traits through effects on RNA processing, including effects on pre-mRNA splicing, 3′ end formation, and RNA stability, localization, structure and ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...

These fatty bubbles are bioengineering wonders with multiple components. Some of these grab onto the mRNA; others stabilize the overall structure. A bit of cholesterol and other modified lipids lower ...

This lipid's structure influences the ability of LNPs to successfully deliver their contents and advances mRNA therapies for vaccines and gene editing. Nanoparticles have transformed how mRNA ...