Rapid-eye-movement (REM) sleep is associated with more sympathetic activation than is NONREM sleep 1,2. So far, there are no data regarding vascular tone during REM and NONREM sleep in humans.

Pressor effects by direct alpha-and beta-adrenergic receptor activation are mediated by ... is caused by norepinephrine release from sympathetic nerves. MAOIs during or within 14 days: avoid.