A groundbreaking review highlights significant advancements in the understanding and treatment of cerebral vascular ...
This mechanism regulates proteostasis across tissues by modulating TGF-β signaling, a pathway involved in cell growth, differentiation, and tissue homeostasis. This breakthrough opens exciting ...
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Researchers find new techniques to repair lung tissue after damage from flu and COVID-19More information: Gan Zhao et al, TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue, Science Translational Medicine (2024). DOI: 10.1126 ...
Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...
Diabetes researchers and bioinformaticians from the Icahn School of Medicine at Mount Sinai ... that DYRK1A inhibitors can synergize with TGF-beta signaling as well as GLP-1 receptor agonist ...
For distinguished contributions to the field of cancer biology, particularly in TGF-beta signaling, and for tireless mentorship and service. The new fellows will receive official recognition during ...
Aberrant TGF-β signaling and EMT are implicated in renal fibrosis ... in lung cancer metastasis as revealed by sngle-cell analysis (from Laughney et al Nature Medicine 2020) A metastasis initiating ...
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