Topiramate is under clinical development by CURx Pharmaceuticals and currently in Phase I for Epilepsy. According to GlobalData, Phase I drugs for Epilepsy have an 84% phase transition success rate ...

Topiramate, an antiepileptic drug with potential mechanisms of action including sodium channel blockade, inhibition of glutamate receptors, and enhancement of γ-aminobutyric acid (GABA ...

The anticonvulsant topiramate causes dose-dependent weight loss in humans and in animal models of diabetes. Toplak and colleagues, therefore, investigated the efficacy and safety of topiramate as ...

The dosage for Topamax (topiramate) may depend on its use. To help prevent migraines, the recommended starting dosage is 25 milligrams (mg) per day. To treat seizures, the typical starting dosage ...

Significant difference between controls and topiramate augmentation group (< 0.05) ** Significant difference between controls and topiramate augmentation group (< 0.01) + Significant difference ...

Medically reviewed by Kristie Reed, PharmD Topamax (topiramate) is an anti-seizure medication that may be prescribed to ...

Several studies have demonstrated topiramate's efficacy in improving drinking behaviour and maintaining abstinence. The objective of the present open-label controlled study was to assess efficacy ...