Topiramate, an antiepileptic drug with potential mechanisms of action including sodium channel blockade, inhibition of glutamate receptors, and enhancement of γ-aminobutyric acid (GABA ...

The anticonvulsant topiramate causes dose-dependent weight loss in humans and in animal models of diabetes. Toplak and colleagues, therefore, investigated the efficacy and safety of topiramate as ...

Medically reviewed by Kristie Reed, PharmD Topamax (topiramate) is an anti-seizure medication that may be prescribed to ...

For the first week of treatment, the highest possible starting dose is 25 mg/day, taken in the evening. Your child’s dose will be 1 to 3 mg of Topamax per kg of body weight (mg/kg), up to the ...

Several studies have demonstrated topiramate's efficacy in improving drinking behaviour and maintaining abstinence. The objective of the present open-label controlled study was to assess efficacy ...

The metabolic adverse effects of topiramate have been well documented in the pediatric population, [4,5] but case reports in the adult population are limited. [6,7,8,9,10,11] Published reports ...