RNA cleavage can occur either: (i) by a transesterification mechanism that yields 2’,3’-cyclic-PO 4 and 5’-OH ends; or (ii) via a hydrolytic mechanism that leaves 3’-OH and 5’-PO 4 ends. RNA repair ...

Image Credit: ABB Inc. PVA is synthesized via hydrolysis via polyvinyl acetate (PVAc), achieved by a base-catalyzed transesterification (e.g., alcoholysis) with alcohol, such as methanol or ethanol.