The discovery of a family of proteins with strong homology to the uncoupling protein of brown ... with respect to body fat mass and islet function, we should not be distracted from the fact ...

Single-cell sequencing unpacked 10 varieties of fat cells, including one that uses an alternative heat-regulating strategy ...

To characterize the contributions of individual amino acids to the structure or function of a protein, researchers have adopted directed evolution approaches, which use iterated cycles of ...

We compute amino acid sequences predicted to fold into proteins with new structures and functions, produce synthetic genes encoding these sequences, and characterize them experimentally. I will ...

Passarino has also found in his centenarians a revved-up version of a gene for what is called an uncoupling protein ... been conducting studies of brain function and mobility in the elderly.

Authors should provide at the time of submission a short paragraph explaining why their work justifies urgent publication as a Communication. Ideally, a Full paper in Food & Function should follow ...

The molecular basis of phospho-tyrosyl-regulation of Src-family and Syk-family protein tyrosine kinases in signaling pathways is a current focus of the lab. The conformational activation of Src kinase ...

Proteins are essential macromolecules that play a crucial role in virtually all biological processes. They are the building blocks of life, performing a wide range of functions within organisms, from ...

The three-dimensional shape of a protein determines its function. This is because proteins form attachments and interact with many other molecules and structures inside organisms. The shape of a ...

‘We need protein to build and repair tissues such as bones, muscle and cartilage, to make enzymes and hormones, and it’s also needed for healthy immune system function. Protein is key for ...

In a new study, Yale researchers have uncovered two proteins that play a role in this regulation, shedding light on centrosome-related disorders and revealing potential targets for treatment. The ...

Executive function describes a set of cognitive processes and mental skills that help an individual plan, monitor, and successfully execute their goals. The “executive functions,” as they’re ...