as the absence of signs of upper motor neuron dysfunction is inconsistent with a formal ALS diagnosis. Progressive muscular atrophy (PMA) is clinically characterized solely by signs of lower motor ...

Hyperrelexic, overactive or spastic bladder or bowels occur with spinal cord injury at or above T12. The primary characteristic of this type of injury is increased organ spasms. The UMN bladder may ...

Keenan, Elizabeth 2010. Spasticity management, part 3: Surgery and the use of intrathecal baclofen. British Journal of Neuroscience Nursing, Vol. 6, Issue. 1, p. 12.

Motor neuron disease usually refers to amyotrophic lateral sclerosis, but it can also refer to other kind of neurodegenerative disease that affect the motor neurons, such as progressive primary ...

PMA was diagnosed on the basis of presence of pure lower motor neuron findings at the initial visit. Of the 91 patients originally diagnosed with PMA, 20 subsequently developed upper motor neuron ...

Degenerative cervical myelopathy (DCM) is a clinical condition of upper motor neuron lesion signs, that is confirmed with ...

The goal of the research is to identify the somatosensory neuron classes present in the swallow apparatus (e.g. mechano ... The funding will be used to enhance the collaboration between the ...

Dozens of rodents have been generated that model various aspects of ALS, like motor impairment or degeneration of motor neurons. No model recapitulates the human disease perfectly. By organizing ...

It is important to note that, despite upper motor neuron dysfunction, the Babinski reflex remains the normal response of plantar flexion throughout the individual's life. Clonus may or may not be ...

Troche PhD/CCC-SLP, F-ASHA Director and Principal Investigator, Laboratory for the Study of Upper Airway Dysfunction Michelle S. Troche ... Her clinical work has mainly been in the area of Movement ...

Patients do not typically transition to an upper motor neuron bladder or bowels Bladder and bowel anal-rectal sphincter remains flaccid, becomes highly complaint and is characterized by underactivity ...

ALS is caused by the loss of upper motor neurons, located in the brain ... More information: Mari Carmen Pelaez et al, Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that ...