BACH and Williamson 1 claim to have shown that rat liver forms urea from ammonium lactate even when the activity of arginase is inhibited by high concentrations of ornithine 2. They conclude that ...

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.

Cao said the findings from this translational study, also backed by mouse research, underscore the critical role of the urea cycle in understanding severe liver diseases. "MASLD and MASH are ...

This appears to represent the first of the sequence of reactions leading to urea synthesis. The evidence for this step is based on the observation that when liver slices are incubated with ...